Add time:08/21/2019         Source:sciencedirect.com

In the context of formation of new aza analogs of camptothecin, nitration then reduction of condensed pyridones was realized, leading to new derivatives of pyrrolo-aza-indoles. Treatment of these compounds with hydrobromic acid led to new structure rearrangements while oxidation of the α-position was unsuccessful. Mechanisms of formation of the new products are discussed.

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