Add time:08/27/2019         Source:sciencedirect.com

A dicyano-methylene-4H-pyran (DCM)-based fluorescent probe DCPOP was designed for detecting lysozyme in urine sample. DCPOP showed obvious NIR emission (> 650 nm) avoiding the background fluorescence of urine (450 ˜ 600 nm). Compared to its mimic (DCPO), DCPOP has a big end-capped Triphenyl phosphate (cas 115-86-6) (TPP) moiety, which induced good stability in several aqueous with different pH value. Furthermore, the end-capped TPP moiety showed weak interaction with lysozyme, which could modulate the emission signals of DCPOP. As a result, DCPOP could detect the lysozyme in both PBS buffer and real urine samples.

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