Add time:08/26/2019         Source:sciencedirect.com

FENSULFOTHION (cas 115-90-2), O,O-diethyl O-[p-(methylsulfinyl)phenyl] phosphorothioate, an organophosphorus pesticide, inhibits the activity but not the de novo synthesis of acetylcholinesterase in pea (Pisum sativum) roots. The rate of incorporation of labeled amino acids from 14C-labeled chlorella protein hydrolysate into acetylcholinesterase is affected by the light conditions under which the seedlings are grown. The de novo synthesis of acetylcholinesterase is increased when the seedlings are continuously irradiated with far-red (730 nm) light and is decreased when the plants are grown in total darkness. The pesticide affects acetylcholinesterase synthesis when the seedlings are continuously illuminated with far-red or red (660 nm) light, but has no influence on its synthesis in dark-grown as well as in white (18-hr light and 6-hr dark cycle) light-exposed seedlings. Curiously, far-red irradiation increases the de novo synthesis of acetylcholinesterase when compared to its influence on the total protein synthesis. In the presence of fensulfothion it decreases the synthesis of acetylcholinesterase, but has no significant effect on the total protein synthesis.

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