Synthesis of ethyl N-(diphenyl)methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylates-Science-Chemical Encyclopedia-lookchem

Synthesis of ethyl N-(diphenyl)methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylates
Add time:07/13/2019 Source:sciencedirect.com

A concise method for the synthesis of 1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid derivatives from α,α′-dibromo-o-xylenes via sequential C-alkylation and N-alkylation of a glycine anion is described.

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