A concise synthesis of HIV integrase inhibitors bearing the dipyridone acid motif-Science-Chemical Encyclopedia-lookchem

A concise synthesis of HIV integrase inhibitors bearing the dipyridone acid motif
Add time:08/25/2019 Source:sciencedirect.com

An efficient route to dipyridone acid HIV integrase inhibitors is developed. The key steps include a one-pot three-step formation of the core template (containing one point of structural diversity) followed by a regioselective benzylation and in situ deprotection to afford the title compounds.

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