Add time:08/24/2019         Source:sciencedirect.com

Chiral cyclic α,α-disubstituted α-amino acids with four chiral centers at their acetal moieties were synthesized. An X-ray crystallographic analysis of homo-chiral tripeptide with (2R,3R)-butane-2,3-diol acetal moieties revealed that the tripeptide formed both (P) and (M) helical structures, and all peptide main-chain N(i)–H were intramolecularly hydrogen-bonded with the side-chain acetal –O– of the same amino acid residues (i). The effect of the four chiral centers in the amino acid residue on the peptide backbone helical-screw control was very weak.

We also recommend Trading Suppliers and Manufacturers of Cbz-R-3-Aminoisobutyric acid (cas 132696-46-9). Pls Click Website Link as below: cas 132696-46-9 suppliers