Add time:08/27/2019         Source:sciencedirect.com

A series of N-(3-(4-hydroxyphenyl)-propenoyl)-amino acid tryptamides was based on a previously reported new SIRT2 inhibitor from our group, and it was designed to study if the molecular size of the compound could be reduced. The most potent compounds, N-(3-(4-hydroxyphenyl)-propenoyl)-2-aminoisobutyric acid tryptamide and N-(3-(4-hydroxyphenyl)-propenoyl)-l-alanine tryptamide, were equipotent, 30% smaller in molecular weight, and slightly more selective (SIRT2/SIRT1) than the parent compound.

We also recommend Trading Suppliers and Manufacturers of Cbz-R-3-Aminoisobutyric acid (cas 132696-46-9). Pls Click Website Link as below: cas 132696-46-9 suppliers