Add time:08/26/2019 Source:sciencedirect.com
A simple 3-step method for the introduction of a 3,3-dimethylallyl unit ortho to a phenolic OH group is described. 7-Hydroxycoumarin, 1, was converted to its 1,1-dimethylallyl ether, 5, by reaction with 3-chloro-3-methylbutyne followed by partial hydrogenation. Pyrolysis of 5 gave mainly the C-8 Claisen rearrangement product, osthenol, 10, and also the C-6 isomer, 14. In a similar manner, coumurrayin, 13, was prepared from 5-methoxy-7-hydroxycoumarin in 57 % overall yield.
We also recommend Trading Suppliers and Manufacturers of Coumurrayin (cas 17245-25-9). Pls Click Website Link as below: cas 17245-25-9 suppliers
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View