Add time:08/26/2019         Source:sciencedirect.com

An efficient acylative kinetic resolution of racemic aromatic β-hydroxy esters with cyclohexanecarboxylic anhydride was achieved using newly designed (R)-N-methylbenzoguanidine ((R)-NMBG) derivatives. A series of (R)-NMBG derivatives was synthesized by modifying the original (R)-NMBG catalyst with the introduction of branched N-substituents containing a stereogenic center, and their catalytic performance was evaluated. (R,R)-N-(1-(β-1-Naphthyl)ethyl)benzoguanidine [(R,R)-NβNpEtBG] was found to function as an efficient acyl transfer catalyst for the reaction of a broad variety of substrates, regardless of the substituent type and substitution pattern.

We also recommend Trading Suppliers and Manufacturers of Cyclohexanecarboxylic acid, 4-oxo-1-phenyl-, ethyl ester (cas 108299-25-8). Pls Click Website Link as below: cas 108299-25-8 suppliers