Add time:08/29/2019         Source:sciencedirect.com

Compound 1 is a uniquely substituted ketone prepared via addition of a thiazole anion to an aromatic nitrile in good overall yield. An exploration into the generality of the addition of thiazole anions to nitriles allowed us to make a variety of thiazole ketones in good to excellent yields. The non-odorous thiolate-mediated demethylation reaction used in the synthesis of 1 is also presented.

We also recommend Trading Suppliers and Manufacturers of 4-BROMO-2-(TRIMETHYLSILYL)THIAZOLE (cas 108306-53-2). Pls Click Website Link as below: cas 108306-53-2 suppliers