Add time:08/28/2019         Source:sciencedirect.com

Publisher SummaryThis chapter discusses the properties, distribution, and biosynthesis of pyrroloquinoline quinine (PQQ). PQQ is an essential cofactor for several key enzymes in physiological processes in mammals. Development of inhibitors specifically directed to PQQ might reveal the role of PQQ and quinoproteins, but also that of vitamin B, and enzymes depending on it. This could also be afforded by developing inhibitors specifically blocking the biosynthesis of PQQ or feeding animals a PQQ-free diet. Some analytical procedures are developed to determine PQQ and its derivatives unambiguously in biological materials. The systematic procedures for cofactor identification will stimulate progress on cofactor enzymology. PQQ is detected in several metalloenzymes, which implies that it may also have been overlooked in enzymes already believed to or known to utilize recognized cofactors. The finding of PQQ implies evolutionary variation in the apoprotein of an enzyme and also in its cofactor.

We also recommend Trading Suppliers and Manufacturers of pyrroloquinoline quinone-oxazole (cas 132847-84-8). Pls Click Website Link as below: cas 132847-84-8 suppliers