Add time:08/26/2019         Source:sciencedirect.com

Recent developments in the evolution of more sustainable solvent use in organic synthesis are critically reviewed. Commonly used organic solvents and less common bio-based examples are assessed and ranked on the basis of waste disposal and environmental impact, health and safety parameters. The use of water as a solvent, including the use of aqueous biphasic catalysis, micelle-enabled catalysis and biocatalysis, constitutes a viable, green and sustainable alternative to reactions in organic solvents.

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