Add time:08/26/2019 Source:sciencedirect.com
This paper presents a methodology of oxidative cascade cyclisation of 2-Aminobenzoic acid (cas 118-92-3)s and arylaldehyde using I2 as a catalyst and an environmentally benign oxidant oxone. This method displays facile access to a diverse range of substituted aryl 4H-3,1-benzoxazin-4-ones. This synthetic methodology has many advantages such as: (1) easy availability of starting material, (2) transition metal-free condition (3) use of an environmentally benign oxidant.
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