Carbonylation of 2-chloro-4,6-dimethoxypyrimidine and 2-(chloromethy)-4,6-dimethoxypyrimidine-Science-Chemical Encyclopedia-lookchem

Carbonylation of 2-chloro-4,6-dimethoxypyrimidine and 2-(chloromethy)-4,6-dimethoxypyrimidine
Add time:08/27/2019 Source:sciencedirect.com

The preparation of pyrimidine-2-carboxylates and 2-pyrimidineacetates by alkoxycarbonylation of respectively 2-chloropyrimidine and 2-(chloromethyl)pyrimidine with carbon monoxide in the presence of palladium acetate and 1,1′-bis(diphenylphosphino)ferrocene is described. The new process uses readily available starting materials and affords the corresponding esters in good yields.

We also recommend Trading Suppliers and Manufacturers of 2-Chloromethyl-4,6-dimethoxypyrimidine (cas 114108-86-0). Pls Click Website Link as below: cas 114108-86-0 suppliers

Prev:Highly regioselective and metal-free γ-addition of β-keto esters to isatins, catalyzed by DABCO: direct access to novel class of diversely functionalized 3-hydroxy-2-oxindole scaffolds
Next: Oxidative deamination of L-cystine by L-amino acid oxidase from snake venom: Formation of S-(2-oxo-2-carboxyethylthio)cysteine and S-(carboxymethylthio)cysteine)

Click to view details

Encyclopedia