Synthesis of p-trifluoroacetamidophenyl 3,6-di-O-{2-O-[α-d-mannopyranosyl 6-(disodium phosphate)]-α-d-mannopyranosyl}-α-d-mannopyranoside-Science-Chemical Encyclopedia-lookchem

Synthesis of p-trifluoroacetamidophenyl 3,6-di-O-{2-O-[α-d-mannopyranosyl 6-(disodium phosphate)]-α-d-mannopyranosyl}-α-d-mannopyranoside
Add time:09/01/2019 Source:sciencedirect.com

Reaction of p-trifluoroacetamidophenyl 2,4-di-O-benzyl-α-d-mannopyranoside with 2-O-acetyl-3,4,6-tri-O-benzyl-α-d-mannopyranosyl chloride gave a trisaccharide derivative which was O-deacetylated and then treated with ethyl 2,3,4-tri-O-benzyl-6-O-dibenzyloxyphosphoryl-1-thio-α-d- mannopyranoside. The resulting pentasaccharide derivative was deprotected to yield the title compound which represents a part of the recognition marker on lysosomal enzymes.

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