Add time:08/28/2019         Source:sciencedirect.com

Synthesis of substituted 10,10-dimethyl-7-phenyl-9,10,11,12-tetrahydrobenzo[c]acridin-8(7H)-one derivatives proceeded by the one-pot reaction of aromatic aldehydes, 5,5-dimethylcyclohexane-1,3-dione (dimedone) and 1-naphthylamine, in the presence of Succinimide-N-sulfonic acid (SuSA) has been reported. Simplicity of operation, high yields, easy work-up and a wide range of substrate applicabilities are the key advantages of this methodology. Furthermore, the catalyst can be recovered conveniently and reused efficiently.

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