Add time:09/06/2019         Source:sciencedirect.com

The dissociation of an in vivo ISOSAFROLE (cas 120-58-1) metabolite-cytochrome P-450 complex by a number of exogenous and endogenous compounds is described. The rate of dissociation is temperature-dependent, but the process does not require oxygen. Compounds which produce Type I (substrate) binding spectra with oxidized cytochrome P-450 facilitate displacement of the isosafrole metabolite from cytochrome P-450 whereas Type II (ligand-binding) compounds do not dissociate the complex. The factors necessary for dissociation of the complex are discussed and a model for the isosafrole metabolite-cytochrome P-450 complex is proposed.

We also recommend Trading Suppliers and Manufacturers of ISOSAFROLE (cas 120-58-1). Pls Click Website Link as below: cas 120-58-1 suppliers