Add time:08/28/2019 Source:sciencedirect.com
Direct transition metal-free arylation of benzene has been achieved using a combination of various aryl halides and N,N′-bis(salicylidene)ethylenediamine as a new ligand and catalyst. This facile one-pot reaction is reported as a new CH functionalization protocol for the synthesis of biaryls. In this research, 18-crown-6 and several Schiff-bases were tested and among them, N,N′-bis(salicylidene)ethylenediamine was found to be a great catalyst for this cross-coupling.
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