Add time:08/31/2019         Source:sciencedirect.com

A simple synthesis of the serum cholesterol depressant 3β-hydroxy-5α-cholest-8(14)-en-15-one (I) is described. The key intermediate, 3β-benzoyloxy-5α-cholesta-8,14-diene (III), was synthesized from cholesterol benzoate (II) with minimal purification of intermediates.

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