Add time:09/01/2019         Source:sciencedirect.com

Generic and additional names: GatifloxacinCAS name: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acidCAS registry #: 112811-59-3Molecular formula: C19H22FN3O4Molecular weight: 375.39Intellectual property rights: Kyorin Pharmaceutical Co.Brand names: Tequin (Bristol-Myers Squibb); Zymar (Allergan)Derivatives: Gatifloxacin is a quinolone/fluoroquinolone antibiotic related to ciprofloxacin, enoxacin, fleroxacin, gemifloxacin, grepafloxacin, levofloxacin, lomefloxacin, moxifloxacin, norfloxacin, ofloxacin, pefloxacin, prulifloxacin, rufloxacin, sparfloxacin, temafloxacin, trovafloxacin and sitafloxacinSolubility: 60 mg/ml at pH 4 [DrugBank]Polarity: Log P 1.81 [DrugBank]Melting point: 182–185ºC [DrugBank]Formulation and optimal human dosage: 400 mg tablets, dose is 400 mg dailyDownload high-res image (18KB)Download full-size image

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