Add time:08/30/2019         Source:sciencedirect.com

The pros and cons of monosodium glutamate (MSG), a common food additive, have been long disputed, whereas the effects of MSG consumption on human intestinal microbiome have not been fully understood. In the present study, metagenomics sequencing was performed to evaluate the effects of MSG on human intestinal microbiota (n = 12) during a four-week experiment. It was observed that MSG consumption did not significantly alter the intestinal microbial community structure and functional features of the subjects. Although some bacteria including Faecalibacterium, Megamonas, Blautia and Collinsella tended to change, there was no significant difference in the alteration of all genera. At the functional level, the microbial functions were rich, mainly distributed in membrane transport, amino acid metabolism and carbohydrate metabolism, but there was no significant difference between samples obtained at different times. Additionally, it was discovered that the impact of the individuals on intestinal microbiota was greater than that of MSG.

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