Add time:08/29/2019         Source:sciencedirect.com

The chemo- and enantioselective reduction of ethyl 4-chloroacetoacetate and the diastereoselective conjugate addition of enantiopure lithium N-benzyl-N-(α-methylbenzyl)amide to an α,β-unsaturated ester have been used as the key steps in the total asymmetric syntheses of (+)-negamycin (in 13 steps and 24% overall yield), (+)-3-epi-negamycin (in 13 steps and 10% overall yield) and sperabillin C (cas 111337-84-9) (in 17 steps and 13% overall yield) from commercially available starting materials.

We also recommend Trading Suppliers and Manufacturers of sperabillin C (cas 111337-84-9). Pls Click Website Link as below: cas 111337-84-9 suppliers