Add time:08/30/2019         Source:sciencedirect.com

A practical, operationally simple preparation of 2-(trimethylsilyl)methyl-2-propen-1-ol derivatives is described. The cobalt catalyzed coupling of a protected vinyl halide with trimethylsilylmethylmagnesium chloride shows excellent functional group tolerance and provides these synthetically useful allyl silanes in good overall yield. By this method, the use of highly concentrated organolithium reagents, complex reaction protocols, and expensive starting materials is avoided.

We also recommend Trading Suppliers and Manufacturers of 1-(Trimethylsilyl)-1-pentyn-3-one (cas 18387-58-1). Pls Click Website Link as below: cas 18387-58-1 suppliers