Add time:09/04/2019         Source:sciencedirect.com

Bis(9-fluorenylmethyl)phosphite (BFMP) was found to be an effective reagent for the N-phosphorylation of various amino acid methyl esters. BFMP was prepared from N,N-diisopropyl phosphoramidous dichloride in a one-pot two-step reaction and was obtained as a crystalline solid. N-Phosphorylation of the methyl esters of seven representative amino acids with BFMP was high-yielding and generally resulted in crystalline products. Complete deprotection of both the 9-fluorenylmethylphosphosphate esters and the amino acid methyl esters was accomplished concomitantly with LiOH to give N-phosphoryl amino acids.

We also recommend Trading Suppliers and Manufacturers of Diisopropyl(phosphoryl)-trans-4-hydroxyprolin (cas 117286-92-7). Pls Click Website Link as below: cas 117286-92-7 suppliers