Add time:09/01/2019 Source:sciencedirect.com
The principal constituents of iris oil, (−)-cis-α-irone and (−)-cis-γ-irone, and their enantiomers, were synthesized from (−)- and (+)-2,2,4-trimethyl-3-cyclohexene-1-carboxylic acids. The racemic acid was resolved by recrystallization of its salt with a chiral amine, or by enzymatic hydrolysis of the corresponding alcohol. The fragrances of (−)-(1R,5S)-cis-α-irone and (−)-(1R,5S)-cis-γ-irone were superior to those of (+)-(1S,5R)-cis-α-irone and (+)-(1S,5R)-cis-γ-irone.
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