Add time:08/31/2019 Source:sciencedirect.com
A single short-term exposure of the peritoneal membrane to N-myristyl-β-aminopropionic acid solution (0.25%) gave an accelerating effect on the peritoneal clearance of salicylate, barbiturate, and diphenylhydantoin, which lasted throughout several subsequent exchanges with standard dialysis fluid. A brief kinetic study on N-myristyl-β-aminopropionate was done, and its intraperitoneal absorption and urinary and peritoneal clearances are reported. The LD50 of this wetting agent in mice and its hemolytic threshold were also estimated.
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