Macrolide biosynthesis: A single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin in Streptomyces venezuelae-Science-Chemical Encyclopedia-lookchem

Macrolide biosynthesis: A single cytochrome P450, PicK, is responsible for the hydroxylations that generate methymycin, neomethymycin, and picromycin (cas 19721-56-3) in Streptomyces venezuelae
Add time:09/02/2019 Source:sciencedirect.com

The final step in the biosynthesis of methymycin, neomethymycin, and picromycin (cas 19721-56-3) is an hydroxylation, shown to be carried out by the cytochrome P-450 monooxygenase, PicK. Direct comparison of the relative kcatKm values for the two substrates, YC-17 and narbomycin, showed a threefold rate preference of picK for narbomycin.

We also recommend Trading Suppliers and Manufacturers of picromycin (cas 19721-56-3). Pls Click Website Link as below: cas 19721-56-3 suppliers

Prev:Macrolactonization to 10-deoxymethynolide catalyzed by the recombinant thioesterase of the picromycin (cas 19721-56-3)/methymycin polyketide synthase
Next: Research PaperFormation of functional heterologous complexes using subunits from the picromycin (cas 19721-56-3), erythromycin and oleandomycin polyketide synthases)

Click to view details

Encyclopedia