Add time:07/12/2019 Source:sciencedirect.com
The steric hindered Aib-Aib-Aib tripeptide was synthesized in mild conditions, using PyBroP for the coupling of two Aib and Fmoc-Aib-NCA for the generation of the tripeptide, which was obtained with an excellent yield in THF. The coupling of Gln was carried out in the presence of BOP.
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