The stability of methyl-, ethyl- and fluoroethylesters against carboxylesterases in vitro: there is no difference-Science-Chemical Encyclopedia-lookchem

The stability of methyl-, ethyl- and fluoroethylesters against carboxylesterases in vitro: there is no difference
Add time:07/21/2019 Source:sciencedirect.com

IntroductionCarboxylesterases (CES) play a very important role in the hydrophilic biotransformation of a huge number of structurally diverse drugs and especially play a leading part in the catabolic pathway of carboxylesters or thioesters. Hence, the aim of the present study was the comparison of the in vitro stability of methyl- and ethylesters with fluoroethylesters.

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