Synthesis of 2,5-difunctionalised-3,3-dimethylpiperidines via ω-halogenated imines-Science-Chemical Encyclopedia-lookchem

Synthesis of 2,5-difunctionalised-3,3-DIMETHYLPIPERIDINE (cas 1193-12-0)s via ω-halogenated imines
Add time:07/15/2019 Source:sciencedirect.com

2,5-Difunctionalised-3,3-dimethylpiperidines were prepared by addition of nucleophiles to piperideinium salts, formed by electrophile-induced cyclisation of γ,δ-unsaturated imines with N-bromosuccinimide in alcoholic medium.

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