Add time:09/03/2019 Source:sciencedirect.com
d-(+)-Limonene can be converted into the corresponding bicyclic organoborinate intermediate, B-methoxy-4,8-dimethyl-2-borabicyclo[3.3.1]nonane, by cyclic hydroboration with borane in THF, followed by methanolysis, and distillation of the product. Alternatively, cyclic hydroboration of d-(+)-limonene with thexylborane provides the related bicyclic organoborane intermediate, B-thexyl-4,8-dimethyl-2-borabicyclo[3.3.1]nonane. Oxidation of the respective intermediates produces d-(−)-(1R, 2R, 4R)-limonene-2,9-diol. Protonation of the bicyclic thexyl intermediate, followed by oxidation, provides d-(−)-(1R, 2R, 4R)-carvomenthol. These results suggest that the cyclic hydroboration of dienes can provide a valuable means for controlling the exact site of hydroboration, leading to a stereoselective synthesis of alcohols.
We also recommend Trading Suppliers and Manufacturers of (1R,4R)-2-Methyl-2,5-diazabicyclo[2.2.1]heptane (cas 133097-95-7). Pls Click Website Link as below: cas 133097-95-7 suppliers
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View