Add time:09/03/2019 Source:sciencedirect.com
In our previous study, the degree of adsorption of 9 representative antimicrobial agents to Toraymyxin® PMX-F sheets was quantitatively evaluated [1]. As a result, the adsorption rate was 22.1% for Linezolid in the presence of serum.Therefore, we investigated whether two types of antimicrobial agents (Ciprofroxacin and Linezolid) can be better adsorbed on PMX-F sheets. When the number of PMX-F sheets was increased in a step wise manner, specifically 2, 4, 6, 8 and 12, the adsorption rate increased linearly.In addition, the adsorption to polymyxin-B immobilized fiber (Toraymyxin® PMX-20R) cartridges, widely used to remove endotoxins from circulating blood in the treatment of sepsis, was quantitatively evaluated. As a result, in the presence of serum, Linezolid showed adsorption to PMX-20R, and the adsorption rate after 2 h was 54.5%, and that after 4 h was 65.8%.The results of this study suggest the necessity of monitoring blood antimicrobial concentration during treatment for sepsis with Linezolid, which showed adsorption to PMX-20R in an environment close to a clinical environment.
We also recommend Trading Suppliers and Manufacturers of (20R)-Pregn-5-ene-3β,12β,14β,20-tetrol (cas 18463-31-5). Pls Click Website Link as below: cas 18463-31-5 suppliers
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View