Add time:09/05/2019 Source:sciencedirect.com
An efficient, general, and racemization free method of covalently attaching N α -Fmoc protected amino acids to solid supports for peptide synthesis is described. The process involves the preparation of 2,4-dichlorophenyl-N α -Fmoc-aminoacyl-4-oxymethyl-phenoxy acetates which can be used to directly and efficiently acylate amine functionalized polymers.
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