Add time:09/03/2019         Source:sciencedirect.com

(6′R)- and (6′S-6′-C-methyl-3-deazaneplanocin A's were synthesized from D-ribose as anti-RNA virus agents. Of these compounds, (6′R)-6′-C-methyl-3-deazaneplanocin A (4b) showed the greatest anti-RNA virus activity in vitro. It was found that the 6′R-configuration was essential for the antiviral activity of 6′-C-methylneplanocin A derivatives.

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