Add time:09/05/2019 Source:sciencedirect.com
This study evaluated the efficacy of two different doses of Amprolium (cas 121-25-5) in goats heavily infected with pathogenic Eimeria species. Forty Boer goat kids ranging from 3 to 5 months of age with naturally occurring coccidiosis were randomly divided into 2 groups and treated orally with amprolium at doses of 10 mg/kg daily for 5 days (n = 20) or 50 mg/kg daily for 5 days (n = 20). The Eimeria oocyst per gram concentrations were significantly reduced on day 7 in the kids that received amprolium at 50 mg/kg, however oocyst concentrations were not significantly reduced in goats that received the 10 mg/kg dose. Out of 100 Eimeria oocysts identified from a pooled fecal sample, E. christenseni was the most frequently identified (52%) coccidial species present. The results of this trial indicate that amprolium can be an effective treatment for pathogenic Eimeria species in goat kids, however higher and extralabel doses (50 mg/kg) should be used.
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