Add time:07/17/2019         Source:sciencedirect.com

Publisher SummaryThis chapter explains the description, physical properties, total synthesis, drug stability, and methods of analysis of homatropine hydrobromide. Examination of the nuclear magnetic resonance (NMR) spectra of some tropane deuterohalides has shown that the N-substituent in tropanes is predominantly equatorial. The ultraviolet (UV) spectrum of homatropine hydrobromide in methanol has been scanned from 200–350 nm using spectrophotometer. The 13C-NMR completely decoupled and off resonance spectra of homatropine hydrobromide are presented in this chapter. Atropine is hydrolyzed with barium hydroxide solution to give tropine and tropic acid. Tropinone can also be synthesized using methylamine hydrochloride acetondicarboxylic acid and generating succindialdehyde in situ by the action of acid on 2,5-dimethoxytetra-hydrofuran. Homatropine is used as a mydriatic and cycloplegic drug in ophthalmology. It is preferred to atropine for diagnostic purposes because its action is more rapid, less prolonged and is more readily controlled by physostigmine.

We also recommend Trading Suppliers and Manufacturers of physostigmine hydrobromide (cas 6091-13-0). Pls Click Website Link as below: cas 6091-13-0 suppliers