Add time:09/06/2019 Source:sciencedirect.com
Three radioactive precursors, [3-3H]-oleanolic acid and its 3-O-monoglucoside and 3-O-monoglucuronide, were administrated to ligulate flowers of Calendula officinalis. The oleanolic acid was glycosylated to the monoglucoside and its derivatives faster than to the monoglucuronide and its derivatives. After administration of each radioactive monoglycosides their hydrolysis to free oleanolic acid as well as further glycosylation was observed. The 3-O-monoglucoside was hydrolysed more extensively than the 3-O-monoglucuronide and in both cases the 3-O-monoglucoside and its derivatives were formed faster than the derivatives of the 3-O-monoglucuronide.
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