Add time:09/05/2019         Source:sciencedirect.com

Semisynthetic modifications at position-12 (ornithine-5-position, hemiaminal function) of mulundocandin were carried out to improve its chemical stability. New carbon–carbon (C–C) and carbon–hydrogen (C–H) linkage at hemiaminal function -12 has been achieved. Lewis acid catalyzed introduction of electron rich aryl group at position-12 of mulundocandin is developed. Synthesized mulundocandin analogues were evaluated for their chemical stability and antifungal activity against C. albicans and A. fumigatus.

We also recommend Trading Suppliers and Manufacturers of Mulundocandin (cas 108351-20-8). Pls Click Website Link as below: cas 108351-20-8 suppliers