Add time:09/06/2019 Source:sciencedirect.com
A new, convenient, one-pot process is presented for the synthesis of 2-oxazolines in high yields (75–94%) via boron esters of N-(2-hydroxyethyl) amides. The procedure involves thermolysis of the boron esters at 240–260 °C, in the presence of solid CaO as an acid scavenger and allows the preparation of oxazolines from hydroxyethyl amides of aliphatic and aromatic monocarboxylic acids.
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