Add time:09/10/2019 Source:sciencedirect.com
A novel structural class of glycogen synthase kinase-3β inhibitors is modeled using quantum mechanics, automated docking, and molecular dynamics simulations. The proposed binding modes identify important hydrogen bonds and salt-bridges with the ATP-binding pocket of the kinase. The modeled complexes justify the observed structure–activity relationships and provide a structural basis for the high selectivity of these inhibitors against cyclin dependent kinase-2.
We also recommend Trading Suppliers and Manufacturers of 1,2,3-TRIAZOLE-4-CARBOXYLIC ACID (cas 16681-70-2). Pls Click Website Link as below: cas 16681-70-2 suppliers
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View