Add time:09/27/2019 Source:sciencedirect.com
The solubilities of three active pharmaceutical ingredients (APIs) in supercritical carbon dioxide were measured in this study using a semi-flow apparatus. These APIs are chlormezanone (C11H12ClNO3S), Metaxalone (cas 1665-48-1) (C12H15NO3) and methocarbamol (C11H15NO5) that are all used as skeletal muscle relaxants. The solubility data are reported for three isotherms at 308.2, 318.2 and 328.2 K, with the pressure range from 12 to 24 MPa. Most solubility data are within the range of 10−6 to 10−4 mole fraction for each API. The crossover phenomena were observed from the experimental results for all three systems. These solubility data satisfied the thermodynamic consistency tests. They were then correlated using three semi-empirical models. With the optimally fitted binary interaction parameters, satisfactory correlation agreement is presented for each binary mixture.
We also recommend Trading Suppliers and Manufacturers of Metaxalone (cas 1665-48-1). Pls Click Website Link as below: cas 1665-48-1 suppliers
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View