Add time:09/10/2019 Source:sciencedirect.com
A novel synthesis of 5-chloroalkyl-2-oxazolidinones from cyclic ethers was demonstrated. Utilizing 5- and 6-membered cyclic ethers as examples, the α-methylaminomethylcyclic ethers were cyclized to 5-(3-chloropropyl)- and 5-(4-chlorobutyl)-3-methyl-2-oxazolidinone, respectively. Several derivatives of each are reported.
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