4-Quinolylmethyl and 1-Naphthylmethyl as Benzyl-type Protecting Groups of Carboxylic Acids Removable by Homogeneous Palladium-Catalyzed Hydrogenolysis-Science-Chemical Encyclopedia-lookchem

4-Quinolylmethyl and 1-Naphthylmethyl as Benzyl-type Protecting Groups of Carboxylic Acids Removable by Homogeneous Palladium-Catalyzed Hydrogenolysis
Add time:07/21/2019 Source:sciencedirect.com

4-Quinolylmethyl (4-QUI) esters are reduced by palladium-catalyzed hydrogenolysis by formate anion. The reaction conditions are compatible with reducible substituents or functional groups as aromatic bromo, alkene, aldehyde, ketone, nitrile, ethyl and benzyl esters. An allyl ester is cleaved selectively in the presence of a 4-QUI ester. 1-Naphthylmethyl (1-NAP) esters of α-amino acids could be deprotected without any racemization by the same methodology.

We also recommend Trading Suppliers and Manufacturers of N-methyl-N-(1-naphthylmethyl)-1,5-diphenyl-1H-pyrazole-4-carboxamide (cas 957493-75-3). Pls Click Website Link as below: cas 957493-75-3 suppliers

Prev:Reaction pathways for the growth of polycyclic aromatic hydrocarbons during the supercritical pyrolysis of n-decane, as determined from doping experiments with 1- and 2-methylnaphthalene
Next: Growth reactions of polycyclic aromatic hydrocarbons during the supercritical pyrolysis of n-decane, as determined from doping experiments with 1-methylphenanthrene and fluorene)

Click to view details

Encyclopedia