Add time:09/24/2019 Source:sciencedirect.com
Racemic N-benzylated-β2, β3, and β2,3-amino acid methyl esters were synthesized and submitted to hydrolysis catalyzed by lipase B from Candida antarctica in organic solvents. Good to excellent enantioselectivities were obtained for β3- and β2,3-amino acid derivatives, whereas the enzyme showed a poor stereoselectivity toward β2-amino acid derivatives.
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