Add time:09/25/2019 Source:sciencedirect.com
Aminoglutethimide is an inhibitor of steroid synthesis in the adrenal cortex, where it inhibits a number of cytochrome P450-mediated steps, including the synthesis of pregnenolone from cholesterol. It also inhibits the cytochrome P450 aromatase enzyme responsible for the conversion of androgens to estrogens …
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