Add time:09/10/2019         Source:sciencedirect.com

The separation of 13 isomeric alkylphenols has been studied by high-performance liquid (HPLC), gas-liquid (GLC) and high-performance thin-layer chromatographic (HPTLC) techniques. It has been shown that the separation of isomeric alkylphenols is dependent upon the adsorption, the polarity of the solvent systems and the configuration of the compounds when using HPLC technique. The separation of all the 13 isomeric alkylphenols by GLC is also possible but the long analysis times and instability of the stationary phase at higher temperatures makes it inferior to HPLC. It has also been shown that HPLC is more powerful than HPTLC. A modification of the injection port for increasing the life of HPLC septa is suggested.

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