Add time:09/27/2019 Source:sciencedirect.com
The potent mutagen 2-bromoacrolein is formed from the carcinogenic flame retardant TRIS(2,3-DIBROMOPROPYL)PHOSPHATE (cas 126-72-7) (Tris-BP) on incubation with hepatic microsomes. Substitution of deuterium for hydrogen at the terminal carbon atoms (C-3) of Tris-BP significantly decreased both the mutagenic response and the formation rate of 2-bromoacrolein. Mass spectral analysis of the 2-bromoacrolein that was formed from the selectively deuterated analogs of Tris-BP revealed that the primary mechanism for the formation of 2-bromoacrolein involves an initial oxidative dehalogenation at C-3 followed by a β-elimination reaction.
We also recommend Trading Suppliers and Manufacturers of TRIS(2,3-DIBROMOPROPYL)PHOSPHATE (cas 126-72-7). Pls Click Website Link as below: cas 126-72-7 suppliers
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View