Add time:09/27/2019 Source:sciencedirect.com
A series of substituted indoloquinolinones were readily synthesized, via two steps, from indole-2-carboxylic acid and its derivatives: a 3-arylation of indole-2-carboxamides and a subsequent PIDA-mediated oxidative C–N bond formation. The underpinning strategy involves a Cu(I)-promoted C(sp2)–C(sp2) coupling and a PIDA-mediated oxidative C(sp2)–N coupling.
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