Add time:07/16/2019         Source:sciencedirect.com

New synthetic pathways have been elaborated to 1-methyl-1H-pyridazino[3,4-b]indoles starting from halopyridazin-3(2H)-ones. Suzuki cross-coupling reaction of chloro, iodo, dichloro, and dibromo substituted pyridazin-3(2H)-ones with 2-pivaloylaminophenylboronic acid followed by hydrolysis of the amide and subsequent ring closure via condensation gave fused indoles. Some of these compounds showed biological activity as antitrypanosomal agents.

We also recommend Trading Suppliers and Manufacturers of 1H-Indole, 4-chloro-7-iodo- (cas 1000341-82-1). Pls Click Website Link as below: cas 1000341-82-1 suppliers