Add time:07/19/2019 Source:sciencedirect.com
A simple and facile synthesis of 5-aryl-5,11-dihydro-1H-indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidine-2,4,6-trione derivatives was accomplished by the one-pot condensation of aromatic aldehydes, 1,3-indandione and 6-amino uracil under solvent-free conditions in the presence of the catalyst, β-cyclodextrin-propyl sulfonic acid (β-CD-PSA). This method has the advantages of high yield, clean reaction, simple methodology, and short reaction time. The catalyst could be recycled and reused four times without significant loss of activity.
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